Phd candidate or postdoc– Genetic determinants of opioid responsiveness

Oslo universitetssykehus

  • Oslo
  • Midlertidlig
  • Fulltid
  • 6 dager siden
About the positionThe Department of Research and Development at the Division of Emergencies and Critical Care, Oslo University Hospital in collaboration with Leknes Affective Brain lab (www.affectivebrains.com) and the NorOp research team (www.norop.net), offers a unique interdisciplinary project with both clinical and basic science elements. The position (as either PhD candidate or postdoc) is open to candidates with a background in medicine, psychology, neuroscience or nursing and experience with relevant research.The candidate will be part of an interdisciplinary and ambitious research environment that prioritises scientific development, collaboration and support throughout the project period.The candidate would be responsible for conducting a research project on testing the efficacy of a combined mu- and kappa-opioid agonist (pentazocine) in a population with genetic insensitivity to mu-opioid drug (randomized controlled trial (RCT)) in close collaboration with several colleagues in the research group.To apply, please enclose an application letter that outlines the candidate's motivation to work within the Leknes Affective Brain lab, and how their competence matches the project. The project proposal can be made available to applicants upon request.The position is a temporary position as a PhD candidate or postdoc of 3 years duration at 100% position, alternatively 6 years at 50% if needed.Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!Key informationApplication deadline:20.09.2025Employer:Oslo universitetssykehus HFTown/city:OsloTitle:Phd candidate or postdocPositions:1Full-time/part-time:Full-timeEmployment type:Educational positionPercentage of full-time:100Webcruiter ID:5008017264Social sharing :Tasks and responsibilities
  • Prepare materials for ethical approval of a randomized controlled trial
  • Liaise with collaborators to identify and recruit mutation carriers and controls
  • Conduct experimental pain testing within the RCT
  • Analyze behavioural and physiological data
  • Take part in weekly lab meeting
  • Present results at conferences and in written manuscripts for scientific publication
  • Complete mandatory courses and other requirements of the UiO PhD programme
Qualifications
  • Masters (or, for postdoc position, PhD) degree in psychology, medicine, nursing, neuroscience or other relevant fields
  • Documented research experience in topics relevant to the research project (for postdocs, relevant academic papers in respected journals)
  • Experience with (or, for medical doctors, interest in and ability to learn) quantitative research methods and statistical analysis, e.g. in R or other software
  • Experience with analysing large-scale data (e.g. national registries), conducting experimental laboratory studies of pain or stress, and/or conducting RCTs would be an advantage
  • Excellent spoken and written English
Personal qualities
  • Strong motivation for research
  • Curious, ambitious, and well organized
  • Ability to collaborate closely in a large, interdisciplinary team
What we offer
  • A cutting-edge, interdisciplinary, yet clinically grounded project on opioid and non-opioid pain regulatory systems in the human brain
  • Close collaboration with 1-2 postdocs at UiO, anaesthetic scientists at OUS, and the main supervisor, neuroscientist
  • Access to necessary infrastructure at UiO and OUS
  • Possibility to attend courses and international conferences
  • Possibility to combine research and clinical work (50% position over six years may be possible)
Address: Oslo universitetssykehus, Ullevål, Kirkeveien 166, 0450 Oslo, NorwayContactsSiri LeknesProfessorEmail: siri.leknes@psykologi.uio.noLeiv Arne RosselandHead of DepartmentAbout the employerOslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia's largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.

Oslo universitetssykehus