Post-doctoral fellow/ Researcher in cancer epigenomics

Universitetet i Oslo

Oslo
kr 575.400-667.700 pr år
Fast
Fulltid

2 måneder siden

Post-doctoral fellow/ Researcher in cancer epigenomicsJob descriptionA two-year extendable post-doc/researcher position funded by the Norwegian Cancer Society is available in the group of Dr. Biswajyoti Sahu at the Centre for Molecular Medicine (NCMM, Nordic EMBL partnership institute), Faculty of Medicine, University of Oslo, Norway. We are seeking a highly motivated and talented experimental wet-lab scientist for working in the field of cancer epigenomics and transcriptional regulation.Our group investigates the role of transcription factors in human diseases using modern genome-wide methods for regulatory genomic features and chromatin architecture. The project involves working with mammalian cell lines, 3D organoid cultures and stem cell-based methods. We utilize a wide range of cutting-edge genome-wide approaches, from ChIP-seq, CUT&RUN and HiChIP to single-nuclei multiome RNA-seq and ATAC-seq assays, epigenetics analysis using Illumina and single-molecule nanopore sequencing, as well as CRISPR-based approaches for genome editing. We offer a position in an ambitious and inter-disciplinary team and an exciting project focusing on the role of transcription factors and enhancer malfunction in development of enhanceropathies such as cancer.Personal skills

Qualification requirementsWe seek highly motivated individuals with an excellent track record and a strong drive for academic research. Ideal candidate will have:

A PhD degree in any relevant field of life sciences with at least one published first-author paper (for the Postdoctoral fellow, position code 1352) OR
A PhD degree in any relevant field of life sciences with a successfully completed post-doctoral period with a strong publication record in peer-reviewed journals (for the Researcher, position code 1109)
Proven, documented research experience in one or more of the following fields: transcriptional regulation, cancer research, stem cell biology, functional genomics and/or epigenomics (bulk/single-cell)
Prior experience in mammalian cell-based assays, genomic methods like chromatin immunoprecipitation, RNA-seq, ATAC-seq techniques is desirable.
Working experience with organoid culture system and mouse models is considered desirable
Generation and/or analysis of high-throughput omics datasets is desirable, although not mandatory
Excellent written and oral communication skills in English

Ability to work independently and to operate as a team player in multi-disciplinary projects is a must, and willingness to supervise students and staff is important. A good understanding of biochemistry and molecular biology, genomics experiments and bioinformatics is expected, and knowledge about relevant data analysis is considered a plus. Candidates with strong publication record will be given preference.We offer

Salary NOK 575 400 - 667 700 per annum depending on qualifications
An exciting project utilizing cutting-edge genomics methods to understand molecular basis of cancer
A position in an ambitious, multi-disciplinary and well-resourced group that is comprised of both wet-lab and computational scientists
Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

For more information about our current research operations and our latest publications (including Fei et al. Developmental Cell 2023; Karttunen and Patel et al, Nature Communications 2023, Sahu et al, Nature Genetics, 2022; Sahu et al, Oncogene, 2021), see h . The position is offered in our well-funded and modern fully equipped laboratory in NCMM located in the Oslo Science Park near Blindern campus of University of Oslo. The advertised position will start from beginning of April 2024 or as soon as possible.How to applyThe application must include

Cover Letter stating motivation, research interests and work experience.
A recent CV with a complete list of scientific publications
Copies of certificates and grades with explanation of the grading system
Two–three reference letters in addition to the contact details of the referees (name, relation to candidate, e-mail and telephone number)

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English. PDF copies of published manuscripts and other course work certificates are not required (provide this information in the list of publications in your CV).Interviews with the best qualified candidates will be arranged. Applications will be considered on a rolling basis till a suitable candidate is found and expected to join as soon as possible.Interviews with the best qualified candidates will be arranged. It is expected that the successful candidate will be able to complete the project in the course of the period of employment.Formal regulationsPlease see the for appointments to Postdoctoral fellowships at the University of Oslo.No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.Contact informationInquiries about the positions can be directed to Group Leader Dr. Biswajyoti Sahu:Inquiries about application can be directed to HR-adviser Nina Modahl:About the University of OsloThe University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7 500 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Universitetet i Oslo

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